Modify DNA Scientists have approved gene editing techniques for human embryos-pp点点通2006

Modify DNA? Scientists have approved the research on human embryonic gene editing technology for fertilized eggs (upper left) divide and grow into blastocysts (lower right) of Sina Technology News Beijing on February 3rd news, British scientists recently approved growth regulators, won the right to modify the gene of human embryos. The research will be carried out at the Francis Institute in London (Francis Crick Institute), and scientists hope to gain a deeper understanding of the early stages of human life with this study. The experiment lasted for 7 days after fertilization. It helps us figure out what’s wrong with what leads to abortion. However, if scientists try to implant such embryos into women, they will be considered illegal. Gene editing is the manipulation of our DNA – the blueprint of life. Last year, Chinese scientists announced for the first time that they had successfully implemented gene editing techniques on human embryos, and modified a gene that causes blood diseases. This area is controversial, some people think that the modification of human embryo genetic this step towards too much, will lead to "designer babies". Infertility earlier this year, Casey? Niyaken Dr. (Kathy Niakan) an explanation for his application to carry out human embryonic gene editing project: "we want to know which genes of human embryos really need to succeed and develop into healthy fetus." "This is very important, because abortion and infertility have become very common, but our understanding of these issues is still very limited." In every 100 fertilized eggs, fewer than 50 can develop to the earliest blastocyst stage, 25 can be implanted into the uterus, only 13 can survive the first three months of pregnancy. The HFEA has approved scientists’ applications, and they will carry out experiments in the next few months. Paul Nurse, director of the Crick Institute, said, "I’m pleased that HFEA has approved Dr. Naken’s application," Paul said." "Dr. Niyaken very is very important for the understanding of the health development of the embryo, and through the observation on the early stage of human life, improve our understanding on the success rate of in vitro fertilization." In the past ten years, Dr. Naken has been studying human development, and now her focus is on the first 7 days after fertilization. During this time, the fertilized egg develops into a structure called blastocyst, which contains 200 to 300 cells. But even in the blastula stage, some cells are also assigned specific duties – some of which are used to form the placenta, some to form yolk sacs, and some to develop into embryos themselves. During this period, a part of DNA will be highly active. These genes are likely to dominate the early stages of embryonic development, but their specific role is unclear, and the cause of abortion remains to be understood. Dr. Sarah Chen (Sarah Cha) of University of Edinburgh

修改DNA?科学家获批研究人类胚胎基因编辑技术 图为受精卵(左上)分裂并发育成囊胚(右下)的过程   新浪科技讯 北京时间2月3日消息,英国科学家近日获得了生育监管机构的审批,获权对人类胚胎的基因进行修改。   该研究将在伦敦的弗朗西斯?克里克研究所(Francis Crick Institute)进行,科学家希望借助这次研究,对人类生命的早期阶段获得更深入的了解。   实验时间为受精后的7天之内。它能够帮助我们明白是什么地方出了问题、导致了流产。   不过,如果科学家试图将这样的胚胎植入女性体内,将被视为违法行为。   基因编辑技术就是操纵我们的DNA――生命的蓝图。   去年,中国科学家首次宣布他们成功在人类胚胎身上实施了基因编辑技术,修改了一处会引起血液病的基因。   这一领域目前备受争议,一些人认为修改人类胚胎基因这一步迈得太大了,将导致“设计师婴儿”的出现。   不孕不育   今年早些时候,凯西?尼亚肯博士(Kathy Niakan)解释了自己申请开展人类胚胎基因编辑项目的原因:“我们很想了解人类胚胎究竟需要哪些基因,才能成功发育成健康的胎儿。”   “这件事非常重要,因为流产、不孕不育已经成为了极其普遍的现象,但我们对这些问题的了解仍然非常有限。”   在每100颗受精卵中,只有不到50颗能发育到最早的囊胚期,25颗能被植入到子宫里,只有13颗能挺过怀孕的头三个月。   人工受精与胚胎学管理局(HFEA)批准了科学家的申请,他们将在接下来几个月中开展实验。   克里克研究所主任保罗?纳斯(Paul Nurse)表示:“我很高兴HFEA批准了尼亚肯博士的申请。”   “尼亚肯博士的研究对于理解健康胚胎的发育来说十分非常重要,并将通过观察研究人类生命的早期阶段,增进我们对体外受精成功率的理解。”   在过去十年间,尼亚肯博士一直在研究人类的发育,目前她所关注的重点是受精后的头7天。在这段时间内,受精卵将发育成一种名为囊胚的结构,包含200至300个细胞。   但即使在囊胚期,有些细胞也被安排了特定的职责――有些用来形成胎盘,有些用来形成卵黄囊,有些则用来发育成胚胎本身。   在这一期间,有一部分DNA将会高度活跃。这部分基因很可能主导着胚胎发育的早期阶段,但它们的具体作用目前还不清楚,流产的原因也尚待了解。   爱丁堡大学的莎拉?陈博士(Sarah Chan)表示:“在胚胎研究中使用基因组编辑技术会涉及一些敏感的问题,因此HFEA在批准该研究进行前,对这项研究和它的伦理意蕴进行慎重考虑是非常恰当的。”   “我们应该相信监管机构能够保证科学研究不与社会利益相违背。”(叶子)相关的主题文章: